PT-141 (Bremelanotide) is a cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone. It is studied for its action on the melanocortin system and central pathways governing desire.
Cyclic melanocortin analogue
Central MC4-mediated mechanism
Distinct from vascular agents
PT-141 acts primarily as an agonist at the MC4 receptor in the central nervous system. Unlike peripheral vasodilators, its proposed mechanism is central rather than vascular.
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